PEGylated Mechano Growth Factor.
PEG-MGF is a PEGylated synthetic version of the C-terminal E-peptide of the IGF-1Ec splice variant — commonly called "mechano growth factor." Research interest focuses on its distinct activity profile compared to native IGF-1. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.
PEG-MGF is a PEGylated synthetic version of the C-terminal E-peptide of the IGF-1Ec splice variant — commonly called "mechano growth factor." Research interest focuses on its distinct activity profile compared to native IGF-1.
Published literature describes MGF as activating muscle satellite cells (stem cells) in response to mechanical loading or damage, distinct from the mature IGF-1 peptide produced by alternative splicing of the same gene. The specific receptor target remains uncertain; published data suggests it is not IGF-1R.
PEGylation extends the very short (~5 minute) half-life of native MGF to approximately 72 hours. Not FDA-approved. Widely studied in muscle regeneration research. WADA prohibited (S2).
The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.
PEG-MGF is a 24-residue peptide with molecular formula IGF-1Ec+PEG and molecular weight of approximately 2,900 Da.
The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.
Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).
Look up the full COA for your lot at coa-lookup.html.
All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.
Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).
PEGylation extends the very short (~5 minute) half-life of native MGF to approximately 72 hours. Not FDA-approved. Widely studied in muscle regeneration research. WADA prohibited (S2).
All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.
HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.