⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0010 Peptide Growth Hormone

CJC-1295 (w/DAC)

GHRH analog · albumin-bound.

CJC-1295 with DAC is a synthetic growth hormone-releasing hormone (GHRH) analog engineered for extended serum half-life via covalent albumin binding. The DAC (Drug Affinity Complex) modification is the distinguishing feature — it converts a short-acting peptide into a long-acting one. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — CJC-1295 (W/DAC)
MOLECULAR FORMULA
C165H269N47O46
Peptide · growth hormone class.
MOLECULAR WEIGHT
3,647.3 Da
Monoisotopic / reported mass.
CHAIN LENGTH
30 aa
Primary structure residues.
ORIGIN
Synthetic GHRH analog
Source or discovery context.
STUDIED PATHWAYS
GHRHR
Reported in published literature.
REPORTED HALF-LIFE
~6–8 days
DAC albumin binding extends t½.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
Ac-Tyr–D-Ala–Asp–Ala–Ile–Phe–Thr–Gln–Ser–Tyr–Arg–Lys–Val–Leu–Ala–Gln–Leu–Ser–Ala–Arg–Lys–Leu–Leu–Gln–Asp–Ile–Leu–Ser–Arg-Lys(MAL-DAC)

// GRF(1-29) analog with four amino acid substitutions (D-Ala², Gln⁸, Ala¹⁵, Leu²⁷) for protease resistance, plus a maleimidopropionic acid DAC (Drug Affinity Complex) group at Lys³⁰ that binds covalently to serum albumin in vivo. The DAC modification extends serum half-life from minutes to days.
02

What the literature reports.

CJC-1295 with DAC is a synthetic growth hormone-releasing hormone (GHRH) analog engineered for extended serum half-life via covalent albumin binding. The DAC (Drug Affinity Complex) modification is the distinguishing feature — it converts a short-acting peptide into a long-acting one.

Reported mechanism

CJC-1295 binds the GHRH receptor on anterior pituitary somatotrophs, stimulating pulsatile GH release in published preclinical studies. The DAC modification forms a covalent thioether bond with cysteine-34 of serum albumin within minutes of administration, protecting the peptide from renal clearance and DPP-4 degradation.

Research context

Published literature describes sustained elevations of GH and IGF-1 for up to 7 days following a single dose. The compound is not FDA-approved and is widely available as a research compound. CJC-1295 is on the WADA prohibited list (S2).

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.cjc-1295-dac.CJCD-26-Q2-0033.log
// lot release record
compound CJC-1295 (w/DAC) (C165H269N47O46)
lot.id CJCD-26-Q2-0033
class peptide
mw.theoretical 3,647.3 Da
mw.observed 3,647.3 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

CJC-1295 (w/DAC) is a 30-residue peptide with molecular formula C165H269N47O46 and molecular weight of approximately 3,647.3 Da.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

Published literature describes sustained elevations of GH and IGF-1 for up to 7 days following a single dose. The compound is not FDA-approved and is widely available as a research compound. CJC-1295 is on the WADA prohibited list (S2).

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.