⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0011 Peptide Growth Hormone

CJC-1295 (no DAC)

Modified GRF(1-29).

CJC-1295 without DAC (also known as Modified GRF 1-29) is a truncated GHRH analog with four amino acid substitutions for protease resistance, but without the albumin-binding DAC modification. Often studied alongside its DAC-modified counterpart to compare pulsatile vs. tonic GH stimulation. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — CJC-1295 (NO DAC)
MOLECULAR FORMULA
C152H252N44O42
Peptide · growth hormone class.
MOLECULAR WEIGHT
3,358.9 Da
Monoisotopic / reported mass.
CHAIN LENGTH
29 aa
Primary structure residues.
ORIGIN
Synthetic GHRH analog
Source or discovery context.
STUDIED PATHWAYS
GHRHR
Reported in published literature.
REPORTED HALF-LIFE
~30 min
Short pulsatile activity.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
Tyr–D-Ala–Asp–Ala–Ile–Phe–Thr–Gln–Ser–Tyr–Arg–Lys–Val–Leu–Ala–Gln–Leu–Ser–Ala–Arg–Lys–Leu–Leu–Gln–Asp–Ile–Leu–Ser–Arg

// Also called "Modified GRF 1-29" or "ModGRF(1-29)". Same four protease-resistance substitutions as CJC-1295/DAC (D-Ala², Gln⁸, Ala¹⁵, Leu²⁷) but without the maleimido-albumin binding group. Retains the short pulsatile action of native GHRH.
02

What the literature reports.

CJC-1295 without DAC (also known as Modified GRF 1-29) is a truncated GHRH analog with four amino acid substitutions for protease resistance, but without the albumin-binding DAC modification. Often studied alongside its DAC-modified counterpart to compare pulsatile vs. tonic GH stimulation.

Reported mechanism

Binds the GHRH receptor similarly to CJC-1295/DAC but without extended half-life. Published literature describes a pharmacokinetic profile closer to endogenous GHRH — a short pulse of GH release lasting on the order of 30 minutes to 2 hours.

Research context

Used in preclinical and research settings specifically when a pulsatile rather than sustained GH stimulation profile is desired. Often paired in research protocols with a GH secretagogue receptor agonist such as ipamorelin.

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.cjc-1295-no-dac.CJCN-26-Q2-0051.log
// lot release record
compound CJC-1295 (no DAC) (C152H252N44O42)
lot.id CJCN-26-Q2-0051
class peptide
mw.theoretical 3,358.9 Da
mw.observed 3,358.9 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

CJC-1295 (no DAC) is a 29-residue peptide with molecular formula C152H252N44O42 and molecular weight of approximately 3,358.9 Da.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

Used in preclinical and research settings specifically when a pulsatile rather than sustained GH stimulation profile is desired. Often paired in research protocols with a GH secretagogue receptor agonist such as ipamorelin.

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.