Long R3 IGF-1 analog.
IGF-1 LR3 (Long R3 IGF-1) is a modified recombinant analog of insulin-like growth factor 1 engineered for reduced IGFBP binding and extended half-life. Originally developed for research in cell culture (where IGFBPs in serum interfere with IGF-1 bioavailability). Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.
IGF-1 LR3 (Long R3 IGF-1) is a modified recombinant analog of insulin-like growth factor 1 engineered for reduced IGFBP binding and extended half-life. Originally developed for research in cell culture (where IGFBPs in serum interfere with IGF-1 bioavailability).
IGF-1 LR3 is a full IGF-1 receptor agonist. The LR3 modifications reduce binding to IGF binding proteins 1-6 by approximately 3-fold, increasing free IGF-1 activity roughly 3x compared to native IGF-1. The Arg³ substitution is the major contributor to reduced IGFBP binding.
Widely used in cell and tissue culture research as an IGF-1R agonist that is not sequestered by serum IGFBPs. Not FDA-approved for any indication. WADA prohibited (S2).
The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.
IGF-1 LR3 is a protein (83 amino acids, approximately 9,117.0 Da). Formula: C400H625N111O115S9.
The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.
Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).
Look up the full COA for your lot at coa-lookup.html.
All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.
Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).
Widely used in cell and tissue culture research as an IGF-1R agonist that is not sequestered by serum IGFBPs. Not FDA-approved for any indication. WADA prohibited (S2).
All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.
HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.