⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0019 Protein Growth Hormone

HGH (Somatropin)

Recombinant 191-aa protein.

Human growth hormone (somatropin) is a 191-residue protein produced by recombinant DNA technology, structurally identical to endogenous pituitary hGH. It is among the most widely studied and clinically used peptide hormones. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — HGH (SOMATROPIN)
MOLECULAR FORMULA
C990H1528N262O300S7
Protein · growth hormone class.
MOLECULAR WEIGHT
22,125 Da
Monoisotopic / reported mass.
CHAIN LENGTH
191 aa
Primary structure residues.
ORIGIN
Recombinant E. coli
Source or discovery context.
STUDIED PATHWAYS
GHR (JAK2/STAT5)
Reported in published literature.
REPORTED HALF-LIFE
~20 min
Short t½; daily admin in clinical use.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
Somatropin (full 191-residue human GH sequence, identical to endogenous)

// Recombinant human growth hormone, 191 amino acids, 22,125 Da, two disulfide bonds. Manufactured by recombinant DNA technology in E. coli. Structurally identical to pituitary-derived hGH.
02

What the literature reports.

Human growth hormone (somatropin) is a 191-residue protein produced by recombinant DNA technology, structurally identical to endogenous pituitary hGH. It is among the most widely studied and clinically used peptide hormones.

Reported mechanism

HGH binds the growth hormone receptor, a class I cytokine receptor, triggering receptor dimerization and JAK2 phosphorylation. Downstream signaling through STAT5 drives hepatic IGF-1 synthesis and direct metabolic and proliferative effects on target tissues.

Regulatory status

Multiple recombinant somatropin products are FDA-approved for various indications (pediatric growth failure, adult GH deficiency, Turner syndrome, Prader-Willi, AIDS wasting). The research-grade material supplied by PeptideBros is not intended for clinical use. WADA prohibited (S2).

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.hgh.HGH-26-Q1-0012.log
// lot release record
compound HGH (Somatropin) (C990H1528N262O300S7)
lot.id HGH-26-Q1-0012
class protein
mw.theoretical 22,125 Da
mw.observed 22,125 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

HGH (Somatropin) is a protein (191 amino acids, approximately 22,125 Da). Formula: C990H1528N262O300S7.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

Multiple recombinant somatropin products are FDA-approved for various indications (pediatric growth failure, adult GH deficiency, Turner syndrome, Prader-Willi, AIDS wasting). The research-grade material supplied by PeptideBros is not intended for clinical use. WADA prohibited (S2).

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.