⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0018 Protein Hormone / Reproductive

HMG

Human Menopausal Gonadotropin.

Human menopausal gonadotropin is a purified mixture of FSH and LH from post-menopausal urine — a classical source of gonadotropins used in fertility medicine for decades. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — HMG
MOLECULAR FORMULA
FSH + LH mixture (heterodimers)
Protein · hormone / reproductive class.
MOLECULAR WEIGHT
34,000 Da
Monoisotopic / reported mass.
CHAIN LENGTH
230 aa
Primary structure residues.
ORIGIN
Post-menopausal urine
Source or discovery context.
STUDIED PATHWAYS
FSHR + LHCGR
Reported in published literature.
REPORTED HALF-LIFE
Variable (FSH ~37h, LH ~20m)
Mixture PK.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
Purified mixture of FSH and LH glycoproteins

// Not a single peptide — HMG is a purified mixture of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from post-menopausal urine, typically formulated at ~75 IU of each per vial.
02

What the literature reports.

Human menopausal gonadotropin is a purified mixture of FSH and LH from post-menopausal urine — a classical source of gonadotropins used in fertility medicine for decades.

Reported mechanism

The FSH component stimulates ovarian follicle development or spermatogenesis via FSH receptor signaling. The LH component stimulates steroidogenesis (testosterone in males, ovarian theca cells in females) via LHCGR. Typical HMG preparations contain approximately equal IU of each.

Regulatory status

HMG products (Menopur, Repronex, etc.) are FDA-approved for various fertility indications. Research-grade material is available for non-clinical research only.

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.hmg.HMG-26-Q1-0015.log
// lot release record
compound HMG (FSH/LH)
lot.id HMG-26-Q1-0015
class protein
mw.theoretical 34,000 Da
mw.observed 34,000 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

HMG is a protein (230 amino acids, approximately 34,000 Da). Formula: FSH/LH.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

HMG products (Menopur, Repronex, etc.) are FDA-approved for various fertility indications. Research-grade material is available for non-clinical research only.

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.