⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0017 Protein Hormone / Reproductive

HCG

Human Chorionic Gonadotropin.

Human chorionic gonadotropin is a placental glycoprotein hormone structurally and functionally similar to luteinizing hormone (LH). Clinically important in reproductive medicine; used as a research tool for stimulating gonadal steroidogenesis. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — HCG
MOLECULAR FORMULA
Heterodimer α (92 aa) + β (145 aa)
Protein · hormone / reproductive class.
MOLECULAR WEIGHT
36,700 Da
Monoisotopic / reported mass.
CHAIN LENGTH
237 aa
Primary structure residues.
ORIGIN
Pregnancy-derived / recombinant
Source or discovery context.
STUDIED PATHWAYS
LH/CG receptor
Reported in published literature.
REPORTED HALF-LIFE
~24–36 hr
β-subunit stabilizes.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
Glycoprotein heterodimer (α-subunit + β-hCG subunit)

// A glycoprotein hormone consisting of a common α-subunit (92 aa, shared with LH, FSH, TSH) non-covalently bound to a unique β-subunit (145 aa). Heavily glycosylated with N- and O-linked sugar chains that affect bioactivity and clearance.
02

What the literature reports.

Human chorionic gonadotropin is a placental glycoprotein hormone structurally and functionally similar to luteinizing hormone (LH). Clinically important in reproductive medicine; used as a research tool for stimulating gonadal steroidogenesis.

Reported mechanism

HCG binds the LH/CG receptor (LHCGR) — the same receptor as LH. In males it stimulates Leydig cell testosterone production; in females it supports corpus luteum progesterone production. The long half-life (24-36 hr) vs. LH (~20 min) is a function of the heavily glycosylated β-subunit.

Regulatory status

Multiple HCG products are FDA-approved for various fertility indications (Ovidrel, Pregnyl, etc.). WADA prohibited in males (S2). Research-grade material is available for non-clinical research applications only.

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.hcg.HCG-26-Q1-0033.log
// lot release record
compound HCG (Heterodimer α/β)
lot.id HCG-26-Q1-0033
class protein
mw.theoretical 36,700 Da
mw.observed 36,700 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

HCG is a protein (237 amino acids, approximately 36,700 Da). Formula: Heterodimer α/β.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

Multiple HCG products are FDA-approved for various fertility indications (Ovidrel, Pregnyl, etc.). WADA prohibited in males (S2). Research-grade material is available for non-clinical research applications only.

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.