⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0014 Peptide Antioxidant

Glutathione

Tripeptide · redox cofactor.

Glutathione is the most abundant intracellular antioxidant in mammalian cells and a central cofactor of cellular redox biology. A tripeptide with an unusual γ-linkage between glutamate and cysteine, it exists primarily in the reduced GSH form. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — GLUTATHIONE
MOLECULAR FORMULA
C10H17N3O6S
Peptide · antioxidant class.
MOLECULAR WEIGHT
307.3 Da
Monoisotopic / reported mass.
CHAIN LENGTH
3 aa
Primary structure residues.
ORIGIN
Ubiquitous · synthesized intracellularly
Source or discovery context.
STUDIED PATHWAYS
Redox · glutathione S-transferase
Reported in published literature.
REPORTED HALF-LIFE
Short parenteral
Rapidly consumed.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
γ-Glu–Cys–Gly

// Gamma-glutamyl-cysteinyl-glycine. The γ-linkage between glutamate and cysteine is the unusual structural feature — it's formed between the γ-carboxyl of glutamate (not α-carboxyl as in normal peptide bonds), providing metabolic stability against peptidases.
02

What the literature reports.

Glutathione is the most abundant intracellular antioxidant in mammalian cells and a central cofactor of cellular redox biology. A tripeptide with an unusual γ-linkage between glutamate and cysteine, it exists primarily in the reduced GSH form.

Reported mechanism

Functions as the principal intracellular reducing agent via the thiol group of its cysteine residue. Central to detoxification (glutathione S-transferase conjugation of xenobiotics), antioxidant defense (glutathione peroxidase substrate), and protein function (S-glutathionylation as a redox regulatory modification).

Research and clinical use

Used clinically (IV and oral) for various conditions including Parkinson's disease research, autism research, and liver disease. Bioavailability is generally poor via oral routes; parenteral and liposomal formulations are commonly used in research.

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.glutathione.GSH-26-Q2-0104.log
// lot release record
compound Glutathione (C10H17N3O6S)
lot.id GSH-26-Q2-0104
class peptide
mw.theoretical 307.3 Da
mw.observed 307.3 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

Glutathione is a 3-residue peptide with molecular formula C10H17N3O6S and molecular weight of approximately 307.3 Da.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

Used clinically (IV and oral) for various conditions including Parkinson's disease research, autism research, and liver disease. Bioavailability is generally poor via oral routes; parenteral and liposomal formulations are commonly used in research.

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.