⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0012 Peptide Sleep / Stress

DSIP

Delta Sleep-Inducing Peptide.

DSIP (Delta Sleep-Inducing Peptide) is a 9-residue peptide first isolated from rabbit brain in the 1970s based on its ability to induce delta-wave EEG activity in recipient animals. Despite decades of research, its endogenous role remains incompletely characterized. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — DSIP
MOLECULAR FORMULA
C35H48N10O15
Peptide · sleep / stress class.
MOLECULAR WEIGHT
848.9 Da
Monoisotopic / reported mass.
CHAIN LENGTH
9 aa
Primary structure residues.
ORIGIN
Rabbit brain dialysate
Source or discovery context.
STUDIED PATHWAYS
Reported sleep regulation
Reported in published literature.
REPORTED HALF-LIFE
~20 min
Short t½.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
Trp–Ala–Gly–Gly–Asp–Ala–Ser–Gly–Glu

// Tryptophan-alanine-glycine-glycine-aspartate-alanine-serine-glycine-glutamate. First isolated from rabbit brain dialysate by Monnier and Schoenenberger (1974) based on a bioassay for sleep-inducing activity.
02

What the literature reports.

DSIP (Delta Sleep-Inducing Peptide) is a 9-residue peptide first isolated from rabbit brain in the 1970s based on its ability to induce delta-wave EEG activity in recipient animals. Despite decades of research, its endogenous role remains incompletely characterized.

Reported mechanism

Published literature describes effects on sleep architecture (delta-wave increase), stress response, and possible HPA axis modulation. Proposed receptor targets and binding partners remain incompletely identified — DSIP has been called an "orphan peptide" despite its well-characterized physiological effects.

Research context

Studied extensively in European and Russian research traditions for sleep, stress adaptation, and athletic performance. Not FDA-approved. Widely available as a research compound.

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.dsip.DSIP-26-Q2-0061.log
// lot release record
compound DSIP (C35H48N10O15)
lot.id DSIP-26-Q2-0061
class peptide
mw.theoretical 848.9 Da
mw.observed 848.9 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

DSIP is a 9-residue peptide with molecular formula C35H48N10O15 and molecular weight of approximately 848.9 Da.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

Studied extensively in European and Russian research traditions for sleep, stress adaptation, and athletic performance. Not FDA-approved. Widely available as a research compound.

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.