NNMT inhibitor · small molecule.
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), developed by Calico Labs researchers. NNMT is an enzyme implicated in metabolic disease and aging through its consumption of the NAD+ precursor nicotinamide. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), developed by Calico Labs researchers. NNMT is an enzyme implicated in metabolic disease and aging through its consumption of the NAD+ precursor nicotinamide.
Competitive NNMT inhibitor. NNMT consumes nicotinamide and S-adenosyl methionine to produce 1-methyl-nicotinamide — a reaction that depletes both a key NAD+ precursor and a universal methyl donor. Inhibition is reported to restore nicotinamide availability for NAD+ synthesis and preserve methylation capacity.
A research-stage compound with growing interest in obesity, adipose tissue biology, and metabolic disease. Published preclinical work (primarily in mice) describes reduced adiposity and improved metabolic parameters with chronic administration. Not in clinical trials as of publication.
The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.
5-Amino-1MQ is a small molecule (molecular formula C10H11N2+, MW approximately 159.2 Da) — not a peptide.
The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.
Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).
Look up the full COA for your lot at coa-lookup.html.
All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.
Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).
A research-stage compound with growing interest in obesity, adipose tissue biology, and metabolic disease. Published preclinical work (primarily in mice) describes reduced adiposity and improved metabolic parameters with chronic administration. Not in clinical trials as of publication.
All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.
HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.