α-MSH analog · linear.
Melanotan I (afamelanotide, Scenesse) is a synthetic 13-residue α-melanocyte stimulating hormone analog developed in the late 1980s. The linear peptide retains MC1R activity for pigmentation research while offering improved stability over native α-MSH. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.
Melanotan I (afamelanotide, Scenesse) is a synthetic 13-residue α-melanocyte stimulating hormone analog developed in the late 1980s. The linear peptide retains MC1R activity for pigmentation research while offering improved stability over native α-MSH.
Agonist of all melanocortin receptors (MC1R through MC5R) with highest activity at MC1R in melanocytes. MC1R activation drives cyclic AMP signaling, tyrosinase upregulation, and increased eumelanin synthesis. The D-Phe⁷ substitution is the key modification that increases potency and protease resistance.
FDA-approved as Scenesse (afamelanotide) for erythropoietic protoporphyria (EPP) — a rare inherited condition causing painful photosensitivity. The implant formulation is tightly restricted. Research-grade material is for non-clinical use only.
The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.
Melanotan I is a 13-residue peptide with molecular formula C78H111N21O19 and molecular weight of approximately 1,646.8 Da.
The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.
Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).
Look up the full COA for your lot at coa-lookup.html.
All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.
Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).
FDA-approved as Scenesse (afamelanotide) for erythropoietic protoporphyria (EPP) — a rare inherited condition causing painful photosensitivity. The implant formulation is tightly restricted. Research-grade material is for non-clinical use only.
All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.
HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.