⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0021 Peptide Growth Hormone

Hexarelin

GHS hexapeptide · 2-Me-Trp.

Hexarelin is a synthetic hexapeptide growth hormone secretagogue — structurally similar to GHRP-6 with a methyl substitution that increases ghrelin receptor affinity. Developed by Mediolanum Farmaceutici in Italy. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — HEXARELIN
MOLECULAR FORMULA
C47H58N12O6
Peptide · growth hormone class.
MOLECULAR WEIGHT
887.0 Da
Monoisotopic / reported mass.
CHAIN LENGTH
6 aa
Primary structure residues.
ORIGIN
Synthetic · modified GHRP-6
Source or discovery context.
STUDIED PATHWAYS
GHSR1a · CD36
Reported in published literature.
REPORTED HALF-LIFE
~55 min
Longer than GHRP-6.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
His–D-2-Me-Trp–Ala–Trp–D-Phe–Lys-NH₂

// Histidyl-D-2-methyl-tryptophyl-Ala-Trp-D-Phe-Lys amide. Structurally GHRP-6 with a 2-methyl substitution on D-Trp for increased receptor affinity and metabolic stability.
02

What the literature reports.

Hexarelin is a synthetic hexapeptide growth hormone secretagogue — structurally similar to GHRP-6 with a methyl substitution that increases ghrelin receptor affinity. Developed by Mediolanum Farmaceutici in Italy.

Reported mechanism

Binds GHSR1a with higher affinity than GHRP-6, producing a more robust GH release in published comparative studies. Notably, hexarelin is also reported to bind CD36 scavenger receptor B (non-GH-receptor mediated activity) — a distinguishing property explored in cardiovascular research.

Research context

Investigated both as a GH secretagogue and as a cardioprotective agent in preclinical models via the CD36 pathway. Not FDA-approved. WADA prohibited (S2).

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.hexarelin.HEX-26-Q2-0044.log
// lot release record
compound Hexarelin (C47H58N12O6)
lot.id HEX-26-Q2-0044
class peptide
mw.theoretical 887.0 Da
mw.observed 887.0 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

Hexarelin is a 6-residue peptide with molecular formula C47H58N12O6 and molecular weight of approximately 887.0 Da.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

Investigated both as a GH secretagogue and as a cardioprotective agent in preclinical models via the CD36 pathway. Not FDA-approved. WADA prohibited (S2).

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.