⚠ FOR LABORATORY RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · QUALIFIED RESEARCHERS 21+
// PB-0013 Peptide Longevity

Epitalon

Khavinson tetrapeptide.

Epitalon is a synthetic tetrapeptide developed by Vladimir Khavinson's group as part of a program to identify short peptide bioregulators from endocrine gland extracts. Derived from pineal gland research, it is one of the most widely studied of the "Khavinson peptides." Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.

01

Compound profile.

// CHEMICAL & STRUCTURAL SPEC — EPITALON
MOLECULAR FORMULA
C14H22N4O9
Peptide · longevity class.
MOLECULAR WEIGHT
390.4 Da
Monoisotopic / reported mass.
CHAIN LENGTH
4 aa
Primary structure residues.
ORIGIN
Synthetic · St. Petersburg IBG
Source or discovery context.
STUDIED PATHWAYS
Reported telomerase effects
Reported in published literature.
REPORTED HALF-LIFE
Minutes
Rapid clearance.
HPLC PURITY
99.8%
Minimum release spec · typical >99.9%.
APPEARANCE
White lyo.
White to off-white lyophilized form.
// PRIMARY STRUCTURE
Ala–Glu–Asp–Gly

// Alanyl-glutamyl-aspartyl-glycine. A synthetic peptide developed by Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology based on studies of pineal gland polypeptide extracts (the related natural compound "Epithalamin").
02

What the literature reports.

Epitalon is a synthetic tetrapeptide developed by Vladimir Khavinson's group as part of a program to identify short peptide bioregulators from endocrine gland extracts. Derived from pineal gland research, it is one of the most widely studied of the "Khavinson peptides."

Reported mechanism

Published work (primarily Russian-language literature) describes effects on telomerase activity, telomere length, and circadian regulation in cell culture and animal models. The proposed mechanism involves direct binding to specific DNA sequences, modulating gene expression. These effects have not been independently validated in extensive Western literature.

Research context

Widely available as a research compound. The Khavinson peptide family more broadly has an extensive Russian research literature but limited validation in other countries. Not FDA-approved.

The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.

03

Storage & release.

SHIP TEMP
Ambient
Lyophilized; stable at room temp in transit.
UNOPENED
Refrigerate
Lyophilized, protected from light.
RECONSTITUTED
~28 days
At 2–8°C; never freeze solutions.
RELEASE DOC
COA · per lot
3rd-party analytical · attached at ship.
lab@peptidebros:~$ cat release.epitalon.EPI-26-Q2-0091.log
// lot release record
compound Epitalon (C14H22N4O9)
lot.id EPI-26-Q2-0091
class peptide
mw.theoretical 390.4 Da
mw.observed 390.4 Da  [PASS]
purity.hplc 99.91%  [> 99.5% spec]
endotoxin < 0.125 EU/mL  [PASS]
sterility no growth  [PASS]
release.status RELEASED
04

Common questions.

What's the molecular profile?+

Epitalon is a 4-residue peptide with molecular formula C14H22N4O9 and molecular weight of approximately 390.4 Da.

The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.

How is purity verified?+

Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).

Look up the full COA for your lot at coa-lookup.html.

How is the compound shipped and stored?+

All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.

Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).

Is this compound FDA-approved?+

Widely available as a research compound. The Khavinson peptide family more broadly has an extensive Russian research literature but limited validation in other countries. Not FDA-approved.

All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.

Every lot,
on paper.

HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.