HGF amplifier · peptidomimetic.
Dihexa is a small-molecule peptidomimetic developed at Washington State University from angiotensin IV structure-activity studies. Research interest focuses on its reported effects on cognition and synaptic plasticity via HGF/c-Met signaling amplification. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.
Dihexa is a small-molecule peptidomimetic developed at Washington State University from angiotensin IV structure-activity studies. Research interest focuses on its reported effects on cognition and synaptic plasticity via HGF/c-Met signaling amplification.
Published literature describes Dihexa as an allosteric amplifier of hepatocyte growth factor (HGF) signaling at the c-Met receptor — rather than a direct c-Met agonist. Reported effects include enhanced dendritic spine density, synaptic plasticity, and cognitive performance in rodent models including Alzheimer's disease models.
An investigational research compound. Not FDA-approved. No clinical trials as of publication. Continues to attract interest in cognitive and neurodegenerative disease research.
The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.
Dihexa is a small molecule (molecular formula C22H35N3O4, MW approximately 405.5 Da) — not a peptide.
The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.
Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).
Look up the full COA for your lot at coa-lookup.html.
All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.
Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).
An investigational research compound. Not FDA-approved. No clinical trials as of publication. Continues to attract interest in cognitive and neurodegenerative disease research.
All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.
HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.