Copper-binding tripeptide.
GHK-Cu is a naturally occurring copper-binding tripeptide originally isolated by Pickart from human plasma in the early 1970s. The literature describes it as a signaling molecule involved in tissue remodeling and copper homeostasis. Supplied as research-grade material with 3rd-party HPLC verification and full Certificate of Analysis per lot.
GHK-Cu is a naturally occurring copper-binding tripeptide originally isolated by Pickart from human plasma in the early 1970s. The literature describes it as a signaling molecule involved in tissue remodeling and copper homeostasis.
Published work describes GHK-Cu as a copper(II) chelator that delivers copper to cellular enzymes requiring it as a cofactor (lysyl oxidase, superoxide dismutase). Reported downstream effects include modulation of collagen and elastin synthesis, regulation of matrix metalloproteinase expression, and anti-inflammatory signaling in skin and wound models. Plasma levels of GHK-Cu decline with age.
GHK-Cu is widely used in cosmetic formulations for skin applications. It has been studied in preclinical and some clinical settings for wound healing and skin regeneration. It is not an FDA-approved drug for any systemic indication.
The above summarizes published research literature. This is not medical advice, a protocol, or a recommendation for use. This compound is supplied for laboratory research only.
GHK-Cu is a 3-residue peptide with molecular formula C14H24N6O4·Cu and molecular weight of approximately 402.9 Da.
The full structural data and release specifications are in the Compound Profile section above. Every lot ships with an independently verified Certificate of Analysis.
Each lot is independently verified by a 3rd-party analytical laboratory (STERIS Labs, Alcami Analytical, or equivalent) before release. Release specification is HPLC purity ≥ 99.5% (typical > 99.8%), mass spectrometry identity match within ±0.5 Da, water content < 5.0% Karl Fischer, and endotoxin < 0.25 EU/mL by LAL (USP <85>).
Look up the full COA for your lot at coa-lookup.html.
All compounds ship at ambient temperature in discreet, tamper-evident packaging. Lyophilized peptide powder is stable at room temperature for typical transit windows, which is why research-grade vendors ship this way. Tracked; signature not required.
Store unopened lyophilized product at 2–8°C protected from light. Once reconstituted, most peptides are stable at 2–8°C for approximately 28 days (compound-dependent).
GHK-Cu is widely used in cosmetic formulations for skin applications. It has been studied in preclinical and some clinical settings for wound healing and skin regeneration. It is not an FDA-approved drug for any systemic indication.
All PeptideBros compounds are sold strictly as chemical reference materials for in-vitro laboratory research. They are not for human consumption.
HPLC-verified. Mass-spec confirmed. Ambient-stable transit. The paperwork other vendors hope you never ask for.